Neurobiology of Disease An Experiment of Nature: Brain Anatomy Parallels Cognition and Behavior in Williams Syndrome
نویسندگان
چکیده
Allan L. Reiss,1 Mark A. Eckert,1 Fredric E. Rose,2 Asya Karchemskiy,1 Shelli Kesler,1 Melody Chang,1 Margaret F. Reynolds,1 Hower Kwon,1 and Al Galaburda3 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, 2Laboratory for Cognitive Neuroscience, Salk Institute, La Jolla, California 92037 and 3Harvard Medical School, Department of Neurology, Boston, Massachusetts 02215
منابع مشابه
An experiment of nature: brain anatomy parallels cognition and behavior in Williams syndrome.
Williams syndrome (WS) is a neurogenetic-neurodevelopmental disorder characterized by a highly variable and enigmatic profile of cognitive and behavioral features. Relative to overall intellect, affected individuals demonstrate disproportionately severe visual-spatial deficits and enhanced emotionality and face processing. In this study, high-resolution magnetic resonance imaging data were coll...
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Studies of abnormal populations provide a rare opportunity for examining relationships between cognition, genotype and brain neurobiology, permitting comparisons across these different levels of analysis. In our studies, we investigate individuals with a rare, genetically based disorder called Williams syndrome (WMS) to draw links among these levels. A critical component of such a cross-domain ...
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تاریخ انتشار 2004